Important Notice
This drug is intended for use by licensed veterinarians only. Strictly adhere to dosing guidelines and contraindications. In case of adverse reactions, contact a specialist immediately.
Practical Administration Guide
1
Pre-Administration Preparation
Prepare the animal and workspace
- 12-hour fasting period
- Remove anti-parasitic collar 24 hours prior
- Prepare sterile syringes and needles
- Ensure a calm environment
2
Premedication (15 minutes before)
Administer supportive medications
- Diphenhydramine 1% – 10 mg/kg (antihistamine)
- Atropine 0.1%: dogs – 0.1 mg/kg, cats – 0.05 mg/kg
- Intramuscular or subcutaneous administration
- Wait for onset of action (15 minutes)
3
Solution Preparation
Reconstitute the lyophilizate immediately before use
- Take the vial with lyophilizate
- Inject the full volume of diluent (5 mL)
- Gently shake the vial
- Ensure complete dissolution
4
Dosage Calculation
Calculate the dose based on animal weight and indication
- 1 mL of reconstituted solution contains: 50 mg tiletamine + 50 mg zolazepam
- Dosage depends on animal species
- Consider the intended use
- Do not exceed maximum dose
5
Drug Administration
Administer the drug using aseptic technique
- Intravenous or intramuscular injection
- Follow aseptic protocols
- Monitor the animal after injection
- Be prepared for onset of action
6
Monitoring & Control
Monitor the animals condition
- Onset of effect: dogs 7–8 min (IM), cats 1.5–7 min (IM)
- Duration of anesthesia: 30–90 minutes
- Recovery period: 2–6 hours
- Maintain a calm environment
Dosage Chart
🐕 Dogs
| Indication | IM | IV |
|---|---|---|
| Clinical examination | 7–10 mg/kg | 5 mg/kg |
| Short-term anesthesia | 10–15 mg/kg | 7.5 mg/kg |
| Prolonged anesthesia | 15–25 mg/kg | 10 mg/kg |
🐱 Cats
| Indication | IM | IV |
|---|---|---|
| Clinical examination | 10 mg/kg | 5 mg/kg |
| Prolonged anesthesia | 15 mg/kg | 7.5 mg/kg |
⚠️ Contraindications & Precautions
Absolute Contraindications:
- Pancreatic disorders
- Severe cardiovascular or respiratory impairment
- Pregnancy and cesarean section
- Hypertension
Special Precautions:
- Reduce dose in animals with renal impairment
- Do not use during lactation
- Maximum dose: dogs 30 mg/kg, cats 72 mg/kg
- Store reconstituted solution for max 10 days (2–8°C)