Multicenter Clinical Studies Confirmed High Efficacy of VEZOTIL

Multicenter Clinical Studies Confirmed High Efficacy of VEZOTIL

March 20, 2023
VETSTEM Scientific Department

The results of multicenter clinical studies of VEZOTIL demonstrated exceptional efficacy and safety in anesthesia for small companion animals.

Main study results:

Chief Physician of the Biocontrol Veterinary Clinic, President of VITAR, Head of SHPO, active member of AVA, IVARM, ESG, Candidate of Biological Sciences E.A. Kornyushenkov not only conducted clinical studies of VEZOTIL®, but also generously shared knowledge and experience with colleagues in a webinar format in June 2024; veterinary physician and leading specialist, practicing anesthesiologist-resuscitator S.S. Olenchuk; Igor Leonidovich Alekseev, Senior Anesthesiologist at Skolkovo VET Veterinary Hospital; Dmitry Nikolaevich Egorov, Chief Veterinarian of the Moscow Zoo — each of these specialists has substantial clinical experience, regular practice in providing anesthetic care of varying complexity, and serves not only as a successful veterinary specialist but also as a lecturer in online educational events by VETSTEM LLC for a broad audience of veterinarians.
  • 98% successful anesthetic procedures without complications
  • Average onset time: 3–4 minutes
  • Optimal duration of action: 45–60 minutes
  • Smooth recovery in 96% of cases
  • Minimal risk of adverse effects

More than 500 animals of various breeds and ages participated in the studies across 15 veterinary clinics in Russia. The studies were conducted over 18 months under strict scientific oversight.

Study methodology:

Clinical studies were conducted according to international GCP (Good Clinical Practice) standards. All animals were divided into groups by species, age, and body weight to obtain the most objective results.

Special attention was paid to monitoring vital functions during anesthesia: heart rate, blood pressure, oxygen saturation, and respiratory rate.

Expert conclusions:

“VEZOTIL demonstrated outstanding results across all safety and efficacy categories,” noted lead investigator Professor V.I. Petrov. “The product may become a new gold standard of anesthesia in veterinary practice.”