Chronic Pain Management
Orthopedic Pathologies • 2025
Study Author
Olga V. Zakirova
Veterinary Anesthesiologist
Pain Management Specialist
Qualifications:
- • Certified anesthesiologist
- • Pain management specialization
- • 8+ years experience
- • International conference participant
Research Specialization
This study opens new perspectives for using Vezotil® not only for anesthesia, but also for long-term chronic pain management in animals with orthopedic diseases.
Key areas:
- • Chronic orthopedic pain
- • Postoperative analgesia
- • Multimodal analgesia
- • Animal quality of life
Research Background
The Chronic Pain Problem
Chronic orthopedic pain is a serious problem in veterinary medicine, significantly reducing animal quality of life. Traditional approaches to analgesia don't always provide adequate pain control with long-term use.
Study Objectives
- • Evaluate Vezotil® efficacy for chronic pain
- • Determine optimal application protocols
- • Study long-term use safety
- • Assess impact on animal quality of life
Innovative Approach
- • Use of sub-anesthetic doses
- • Combination with NSAIDs
- • Individualized protocols
- • Pain parameter monitoring
Clinical Protocol
Application Protocol
Initial Phase
- • Dosage: 2-3 mg/kg
- • Route: intramuscular
- • Frequency: every 12 hours
- • Duration: 3-5 days
Maintenance Therapy
- • Dosage: 1-2 mg/kg
- • Route: IM or SC
- • Frequency: every 24 hours
- • Duration: 7-14 days
Monitoring
- • Pain scale assessment
- • Activity monitoring
- • Appetite and behavior
- • Side effects
Application Results
78%
significant improvement
92%
good tolerability
6.2
pain reduction (out of 10)
85%
activity increase
Development Perspectives
Further Research Directions
Clinical aspects:
- • Long-term safety with chronic use
- • Combined protocols with other analgesics
- • Dosage optimization for different pain types
- • Application in other animal species
Scientific aspects:
- • Pharmacokinetics with chronic use
- • Mechanisms of analgesic action
- • Molecular efficacy markers
- • Personalized pain therapy
🔬 Innovative Potential
Using Vezotil® for chronic pain management opens new opportunities in veterinary medicine and may become an alternative to traditional analgesics with an improved safety profile.